(2R)-amino(3-hydroxyphenyl)ethanoic acid
(R)-4-hydroxyphenylglycine
CAS: 25698-27-5
Molecular Formula: C8H9NO3
(2R)-amino(3-hydroxyphenyl)ethanoic acid - Names and Identifiers
| Name | (R)-4-hydroxyphenylglycine |
| Synonyms | D-3-HYDROXYPHENYLGLYCINE) (R)-4-hydroxyphenylglycine (R)-3-Hydroxyphenylglycine (R)-2-(3-Hydroxyphenyl)glycine (2R)-amino(3-hydroxyphenyl)acetic acid (R)-α-Amino-3-hydroxybenzeneacetic acid D-alpha-Amino-3-hydroxyphenylacetic acid (2R)-amino(3-hydroxyphenyl)ethanoic acid (R)-2-amino-2-(3-hydroxyphenyl)acetic acid Benzeneacetic acid, α-amino-3-hydroxy-, (αR)- D-alpha-Amino-alpha-(m-hydroxyphenyl)acetic acid |
| CAS | 25698-27-5 |
| EINECS | 247-191-9 |
| InChI | InChI=1/C8H9NO3/c10-7-3-1-2-6(4-7)9-5-8(11)12/h1-4,9-10H,5H2,(H,11,12) |
(2R)-amino(3-hydroxyphenyl)ethanoic acid - Physico-chemical Properties
| Molecular Formula | C8H9NO3 |
| Molar Mass | 167.16 |
| Density | 1.396±0.06 g/cm3(Predicted) |
| Boling Point | 382.6±32.0 °C(Predicted) |
| Flash Point | 229.2°C |
| Vapor Presure | 4.38E-09mmHg at 25°C |
| pKa | 1.85±0.10(Predicted) |
| Refractive Index | 1.664 |
(2R)-amino(3-hydroxyphenyl)ethanoic acid - Introduction
(R)-4-hydroxyphenylglycine is an organic compound with the chemical structure C8H9NO3. It has a stereocenter and is the (R) enantiomer. The properties of this compound are as follows:
Nature:
-Appearance: White crystalline powder
-Melting Point: about 175-180 ℃
-Solubility: Slightly soluble in water, better soluble in alcohol and Ester solvents
-Optical rotation:[α]D25 = 26.5 ° (water, c = 1)
Use:
(R)-4-hydroxyphenylglycine is an important amino acid analog, which is widely used in medicine and chemical industry. Its Main uses include:
-Drug synthesis: It can be used as an intermediate in the synthesis of antibiotics, antiviral drugs and other biologically active substances.
-Pharmaceutical research: enantioselective products for the synthesis of drugs.
-Chemical industry: As a raw material, it plays the role of catalyst, ligand and intermediate in organic synthesis.
Method:
(R)-4-hydroxyphenylglycine has a variety of synthetic methods, the common ones include:
-Conversion method: A target product is obtained by reacting a reaction precursor compound with a specific catalyst.
-Enzymatic method: Use the catalysis of a specific enzyme to convert the substrate into the target product.
Safety Information:
(R)-4-hydroxyphenylglycine is considered relatively safe under normal conditions of use. However, like all chemical substances, correct operating procedures should be followed and appropriate safety measures should be taken. Take care to avoid inhaling dust, contact with skin and eyes. Personal protective equipment and safety practices should be followed during use and storage.
Nature:
-Appearance: White crystalline powder
-Melting Point: about 175-180 ℃
-Solubility: Slightly soluble in water, better soluble in alcohol and Ester solvents
-Optical rotation:[α]D25 = 26.5 ° (water, c = 1)
Use:
(R)-4-hydroxyphenylglycine is an important amino acid analog, which is widely used in medicine and chemical industry. Its Main uses include:
-Drug synthesis: It can be used as an intermediate in the synthesis of antibiotics, antiviral drugs and other biologically active substances.
-Pharmaceutical research: enantioselective products for the synthesis of drugs.
-Chemical industry: As a raw material, it plays the role of catalyst, ligand and intermediate in organic synthesis.
Method:
(R)-4-hydroxyphenylglycine has a variety of synthetic methods, the common ones include:
-Conversion method: A target product is obtained by reacting a reaction precursor compound with a specific catalyst.
-Enzymatic method: Use the catalysis of a specific enzyme to convert the substrate into the target product.
Safety Information:
(R)-4-hydroxyphenylglycine is considered relatively safe under normal conditions of use. However, like all chemical substances, correct operating procedures should be followed and appropriate safety measures should be taken. Take care to avoid inhaling dust, contact with skin and eyes. Personal protective equipment and safety practices should be followed during use and storage.
Last Update：2024-04-09 20:45:29
